Non odontogenic carcinoma (epithelial)

1. Oral squamous cell carcinoma
2. Verrucous carcinoma
3. Salivary gland carcinoma
   • Mucoepidermoid carcinoma
   • Polymorphous low grade adenocarcinoma
   • Adenoid cystic carcinoma
   • Clear cell carcinoma
   • Acinic ell carcinoma
   • Unspecific adenocarcinoma
   • CA in PSA

Non odontogenic sarcoma (mesenchymal)

1. Fibrosarcoma
2. Angiosarcoma – Kaposi’s sarcoma
3. Osteosarcoma
4. Chondrosarcoma
5. Liposarcoma
6. Leiomyosarcoma
7. Rhabdomyosarcoma
8. Neurofibrosarcoma
9. Lymphoma:
   • Hodgkin’s lymphoma
   • Burkitt’s lymphoma
   • Multiple myeloma

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Leukemia

• Neoplastic proliferation of white blood cells
• Replacement of bone marrow
• Infiltrate organs (spleen and liver)

• ALL – Most common in children
• AML – Most common in adults

Clinical:

• Splenomegaly and hepatomegaly
• Lymphadenopathy
• Mucosal pallor and abnormal gingival bleeding in a child
• Pancytopenia and it’s effects
• Cancer symptoms

Oral effects of acute leukemia:

• Gingival swelling
• Mucosal ulceration
• Leukemic deposits
• Purpura
• Anaemia
• Cervical lymphadenopathy

Diagnosis:

• Bone marrow biopsy
• Peripheral blood film

Dental management of patient with leukemia:

• Extraction should be avoided
• If necessary: Blood grouping, cross matching, blood transfusion and generous antibiotic cover is needed
• Antimicrobial mouth rinses
• Routine dental treatment

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