Neoplasm of both odontogenic epithelium and mesenchyme

Etiology

• Associated with impacted teeth

Clinical

• Slow growing
• Asymptomatic
• Expand jaw

Epidemiology

• Young adults and children

Common site

• Maxilla > Mandible
• Mandible – Molar ramus area

Radiology

• Well circumscribed lesion – surrounded by sclerotic margin
• Unilocular/multilocular
• Associated with crown of impacted teeth
• Radiolucent
• Opaque foci indicates progression to ameloblastic fibro-odontoma

Histology

• Neoplastic odontogenic epithelium + myxomatous CT = resembles dental lamina
• Encapsulated with collagenous tissue
• In fibro-odontoma/dentinoma – hard tissue formation

Management

• Surgical curettage/excision
• Can become malignant – Ameloblastic fibrosarcoma

Difference between ameloblastic fibroma and ameloblastoma

Picture

---

Ameloblastic fibrosarcoma

• Rare malignant variant that can arise from pre-existing ameloblastic fibroma
• Mandible > Maxilla
• Clinical: Pain & parasthesia
• Management: Resection
• Malignancy is locally aggressive with metastatic potential

Picture

---

Odontoameloblastoma

• Ameloblastoma that secretes dental hard tissues

Picture