The development of skin consists formation of:
- Epidermis
- Dermis
- Subcutaneous tissue
- Hair
- Sweat glands
- Sebaceous glands
(I) Epidermis:
- Ectoderm
- Neural crest cells – Form melanoblasts (melanin secreting cells)
(II) Dermis – paraxial mesoderm (dorsal portion) – dermatome (contributes skin, fat and connective tissue)
(III) Subcutaneous tissue – lateral plate mesoderm – somatic layer (most of the skin derived)
(IV) Hairs:
- Solid ectodermal buds sink into underlying mesenchyme
- Forms hair bud, which is invaginated by mesoderm
- Forms hair papilla
- Muscle fibers attach to hair follicles – errector pili muscles
- Hair bulb central cells elongate and keratinize – hair shaft
- Fetus first hair – lanugo hair

(V) Sweat glands:
- Solid ectodermal buds sink into underlying mesenchyme
- Terminal end coils and it canalizes

(VI) Sebaceous glands:
- Side branches of hair follicle buds
- Central cells degenerate forming fatty secretions
Congenital anomalies:
- Ichthyosis – dry scaly skin
- Hypertrichosis – excessive hair
- Atrichia – congenital absence of hair
- Dermoid – cystic swelling along lines of fusion