Odontogenic myxoma

Etiology

  • Origin from dental papilla/follicular mesenchyme

Clinical

  • Rarely pain
  • Slow growing
  • Aggressively invasive
  • Sometimes associated with impacted teeth
  • Expansile lesion
  • Outer cortical plate expansion – leads to perforation
  • If occurs in maxilla, invades maxillary sinus – exophthalmos

Radiology

  • Early: Unilocular
  • Multilocular radiolucency with septae in a “tennis racket” or “honey comb” appearance
  • Poorly defined boundaries

Histology

  • Stellate cells with long process – forms loose meshwork – interspersed with mucoid intercellular CT – which has occasional strands of odontogenic epithelium

Management

  • Aggressive surgical excision – with safe margin of 1.5-2cm
  • Reconstruction
  • Good prognosis – does not metastasize

Picture

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