Peutz Jegher & Plummer Vinson Syndrome

Peutz Jegher Syndrome

Etiology:

  • AD

Clinical:

  • Hereditary intestinal polyposis
  • Pigmentation of face and oral cavity
  • GIT adenocarcinoma

Histology:

  • Melanin granules in basal layer of mucosa

Plummer Vinson Syndrome

  • AKA Paterson-Kelly syndrome
  • Precancerous lesion
  • Angular cheilitis
  • Dysphagia due to oesophageal webs
  • Filiform papillae atrophy
  • Koilonychia
Plummer vinson syndrome clinical presentation

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