Jaw metastases

Pathways of spread:

  • Direct extension
  • Lymphatic/ vascular dissemination
  • Intraspinal seeding (through Batson plexus of veins)

Most frequent sites: Vertebrae, ribs, pelvis, skull

Common sources of jaw metastases: Breast, prostate, lungs, colorectal & kidneys


  • Elderly patient
  • Pain
  • Swelling
  • Loosening of teeth
  • A mass
  • Paraesthesia
  • Hx primary tumour

Histology: Poorly differentiated malignant cells with little resemblance to the tissue of origin,
confirmation usually done with immunohistochemistry

Management: Low survival rates because metastases usually implies that patient is in Stage IV. Most patients do not survive more than 1 yr


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