Etiology:

AD – mutation in adenomatous polyposis coli (APC) gene – located on chromosome 5q21

Clinical:

Triad:

• Potential malignant colorectal polyposis
• Skeletal abnormality – multiple osteoma
• Multiple impacted teeth, supernumerary teeth and odontomas

Diagnosis:

• Blood test – APC gene mutation
• Osteomas and impacted teeth found on radiograph – do lower GIT endoscopy for colon polyps

Management:

• Alleviate symptoms
• Surgical excision of osteomas