Pleomorphic adenoma

  • The commonest salivary gland tumor
  • 60 – 85% of parotid tumours
  • 45 – 50% of minor gland tumors

Most common intra-oral site: Palate (other – parotid)

Incidence: 5th – 6th decades, F = 60% cases

Clinical: A slow growing, painless, rubbery swelling with intact overlying skin

NB: CA in PSA, 3% of tumors

Histology:

  • A mixture of epithelial & mesenchymal components (myxoid, chondroid & mucoid areas, with architectural diversity)
  • Pseudoencapsulated with both intra- and extracapsular nodules representing growth of pseudopodia into the surrounding tissues → high recurrence rate

Diagnosis:

  • FNA
  • Core needle biopsy
  • Radio, US, CT, MRI

Management:

  • Surgical resection
  • Parotid – Superficial or total parotidectomy

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